Prevalence of congenital anomalies at birth among live births in the state of Maranhão from 2001 to 2016: temporal and spatial analysis

ABSTRACT: Objectives: To analyze the prevalence at birth and spatial temporal distribution of congenital anomalies (CAs) among live births in state Maranhão 2001 to 2016. describe demographic, gestational neonatal variables interest. Methods: Ecological, population-based study, using secondary data from Live Birth Information System (SINASC). Annual total per-group CAs was calculated. Spatial analyzes were based on Local Indicators Association (LISA) Moran I Index, interactive maps generated. Demographic, interest available SINASC described group newborns with CAs. Results: 1,831,830 births, 6,110 (33.4/10,000) included. Higher frequencies occurred more recent years. clusters have been observed specific The different between categories considered as risk factors for this outcome. Conclusion: lower than expected major human defects (3%). peak records 2015/2016 is probably related increase caused by infection Zika virus. due variations random small number they are not repeated other Studies like basis establishment CA surveillance programs.